Lornoxicam

Lornoxicam: a Newer NSAID

Pain relieving drugs are one of the most commonly used drugs worldwide either through prescription or as over the counter medication. Non-steroidal anti-inflammatory drugs usually abbreviated as NSAIDs, are the drugs with analgesic, antipyretic and, in higher doses, with antiinflammatory effects. NSAIDs inhibit cyclooxygenase (COX) 1 and 2. So, most of the side effects develop as a result of cy...

Cutaneous pseudolymphoma following administration of lornoxicam.

Lornoxicam Suppositories: In-vitro Formulation and In-vivo Evaluation

The aim of the present study was to formulate lornoxicam into rectal suppositories as a new dosage form, to avoid its reported gastric irritation and to provide a rapid onset of action for children. Suppositories were prepared using fatty bases namely; witepsol H-15, suppocire AML, CM, witepsol E-75 and water soluble bases; mixtures of poly(ethylene glycol), PEGs, with different molecular weigh...

Dissolution enhancement and formulation of rapid-release lornoxicam mini-tablets.

The aim was to enhance the dissolution of lornoxicam (LOR) and to produce mini-tablets with an optimised system to provide a rapid-release multi-particulate formulation. LOR systems were prepared through co-evaporation with either polyethylene glycol 6000 or Pluronic(®) F-68 (PLU) and adsorption onto Neusilin(®) US2 alone or co-adsorption in the presence of different amounts of polysorbate 80. ...

Pre-Emptive Intravenous Paracetamol and Lornoxicam in T hirdMolar Surgery

Backgrounds: The objective of the present study was to compare the postoperative analgesic effects of pre-emptive intravenous (IV) paracetamol, lornoxicam and placebo following third molar surgery. Materials and Methods: This was a prospective, double-blind, randomized, placebo-controlled study where 50 patients had both of their identical impacted mandibular third molars impacted. Before the r...